Unexplained Infertility DiagnosisThere are many tests that your fertility specialist will perform to see what is causing your infertility and to find a fertility treatment option that will help you become pregnant. However, the tests don’t always reveal a clear answer, resulting in the dreaded diagnosis, unexplained infertility. This diagnosis can feel daunting, but it is important to understand that there are many options ahead of you to see success in your journey to parenthood.

Unexplained infertility does have a reason, but it simply has not been discovered yet. First of all, one in five couples will experience unexplained infertility after complete infertility testing, according to Resolve.org. What you may not realize is that number is so high because there are many things that are classified as unexplained infertility, mainly because doctors are not sure why that condition is affecting fertility. For example, here are some conditions classified as unexplained:

Your age can be a factor in not being able to explain what exactly is causing infertility. If you are over age 35, the chance of fertility issues increases and even more when you are over 40.
• If you are diagnosed with mild endometriosis, your infertility is technically unexplained because we do not know what it is about mild endometriosis that causes fertility problems.
• It appears that everything in the fertility process is working, but if there is one weak link that does not present itself during testing, that could be the cause of infertility. Doctors can’t always pinpoint the weakness as well in certain cases.

While there could be a variety of factors causing unexplained infertility, recent studies have pointed to some explanations as to why infertility is occurring. For example, for 80 percent of couples with unexplained infertility in the United Kingdom, a study showed that the cause may be high sperm DNA damage. This factor does not present itself as obviously as sperm deformations, count and motility. To diagnose this as the cause, doctors need a sperm DNA test. Sperm DNA damage that is 15 percent or less is considered normal. But once sperm DNA damage exceeds 25 percent, the chances of successfully conceiving are lowered significantly.

If you have been diagnosed with unexplained infertility, there are many steps you can take. You can seek a second opinion and have your tests redone. You can question whether you may have mild endometriosis and ask for testing. You can also request a sperm DNA test to see if there is significant damage.

If you are still diagnosed with unexplained infertility after taking these steps, consult this Questions to Ask fact sheet from Resolve.org. Also, ask your fertility specialist what other tests and steps you can take to pinpoint a fertility problem without spending more on fertility treatments that may not be the solution to becoming pregnant.


“Unexplained Infertility.” Resolve. Web. 5 Sep. 2015. .

Kearney, Christine. “Cause Of Unexplained Infertility Discovered For 80% Of Couples.” Medical News Today. 15 Nov 2012: 1. Web. 5 Sep. 2015. .